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1

A limited sampling strategy for estimation of the cladribine plasma area under the concentration versus time curve after intermittent i.v. infusion, s.c. injection, and oral administration

J. Liliemark, Freidoun Albertioni, Gunnar Juliusson, Staffan Eksborg

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 178 KB

english, 1996

2

Kidney volume, kidney function, and ambulatory blood pressure in children born extremely preterm with and without nephrocalcinosis

Rakow, Alexander, Laestadius, Åsa, Liliemark, Ulrika, Backheden, Magnus, Legnevall, Lena, Kaiser, Sylvie, Vanpée, Mireille

Journal:

Pediatric Nephrology

Year:

2019

Language:

english

File:

PDF, 689 KB

english, 2019

3

Prognostic significance of proliferative and apoptotic fractions in low grade follicle center cell-derived non-Hodgkin's lymphomas

Magdalena Czader, Joanna Mazur, Mikael Pettersson, Jan Liliemark, Mats Strömberg, Birger Christensson, Bernard Tribukait, Gert Auer, Åke Öst, Anna Porwit

Journal:

Year:

1996

Language:

english

File:

PDF, 1.00 MB

english, 1996

4

Disease-related hypocholesterolemia in patients with hairy cell leukemia. Positive correlation with spleen size but not with tumor cell burden or low density lipoprotein receptor activity

Gunnar Juliusson, Sigurd Vitols, Jan Liliemark

Journal:

Year:

1995

Language:

english

File:

PDF, 530 KB

english, 1995

5

Determination of 2-chloro-2′-deoxyadenosine in human plasma

Jan Liliemark, Birgitta Pettersson, Gunnar Juliusson

Journal:

Biomedical Chromatography

Year:

1991

Language:

english

File:

PDF, 240 KB

english, 1991

6

Pharmacokinetics of cytosine arabinoside in cerebrospinal fluid and of its metabolite in leukemic cells

Albert N. Békássy, Jan Liliemark, Stanislaw Garwicz, Thomas Wiebe, Hans Gulliksson, Curt Peterson

Journal:

Pediatric Blood & Cancer

Year:

1990

Language:

english

File:

PDF, 640 KB

english, 1990

7

Hydrophobicity parameters of 2-chloro-2′-deoxyadenosine and some related analogues and retention in reversed-phase liquid chromatography

Viera Reichelová, Freidoun Albertioni, Jan Liliemark

Journal:

Journal of Chromatography A

Year:

1994

Language:

english

File:

PDF, 694 KB

english, 1994

8

High-performance liquid chromatography with fluorometric detection for monitoring of etoposide and its cis-isomer in plasma and leukaemic cells

Eva Liliemark, Birgitta Pettersson, Curt Peterson, Jan Liliemark

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 439 KB

english, 1995

9

Determination of 2-chloro-2′-deoxyadenosine nucleotides in leukemic cells by ion-pair high-performance liquid chromatography

Viera Reichelova, Freidoun Albertioni, Jan Liliemark

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1996

Language:

english

File:

PDF, 587 KB

english, 1996

10

Bioavailability and bacterial degradation of rectally administered 2-chloro-2′-deoxyadenosine

Jan Liliemark, Freidoun Albertioni, Charlotta Edlund, Gunnar Juliusson

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1995

Language:

english

File:

PDF, 328 KB

english, 1995

11

Liquid chromatographic study of acid stability of 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine, 2-chloro-2′-deoxyadenosine and related analogues

Viera Reichelova, Jan Liliemark, Freidoun Albertioni

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1995

Language:

english

File:

PDF, 264 KB

english, 1995

12

Relationship between cladribine (CDA) plasma, intracellular cladribine-5-triphosphate (CDATP) concentration, deoxycytidine kinase (DCK) and chemotherapeutic activity in chronic lymphocytic leukemia (CLL)

Freidoun Albertioni, Synnöve Lindemalm, Staffan Eriksson, Gunnar Juliusson, Jan Liliemark

Journal:

Clinical Biochemistry

Year:

1997

Language:

english

File:

PDF, 102 KB

english, 1997

13

Real-time RT-PCR for the determination of topoisomerase II mRNA level in leukaemic cells

Rong Zhou, Marianne Frostvik Stolt, Ulrike Kronenwett, Astrid Gruber, Jan Liliemark, Eva Liliemark

Journal:

Leukemia Research

Year:

2002

Language:

english

File:

PDF, 107 KB

english, 2002

14

Determination of etoposide in human plasma and leukemic cells by high-performance liquid chromatography with electrochemical detection

Rong Zhou, Marianne Frostvik-Stolt, Eva Liliemark

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 88 KB

english, 2001

15

Oral cladribine for B-cell chronic lymphocytic leukaemia: report of a phase II trial with a 3-d, 3-weekly schedule in untreated and pretreated patients, and a long-term follow-up of 126 previously untreated patients

Karin Karlsson, Mats Strömberg, Jan Liliemark, André Delannoy, S. A. N. Johnson, Anja Porwit, Eva Kimby, Gerd Lärfars, Ilse Cristiansen, Göran Nilsson, Fredrik Celsing, Gunnel Sundström, Mikaela Luthm

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 385 KB

english, 2002

16

Gain of chromosome 7 marks the progression from indolent to aggressive follicle centre lymphoma and is a common finding in patients with diffuse large B-cell lymphoma: a study by FISH

Bernell, Jacobsson, Liliemark, Hjalmar, Arvidsson, Hast

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 341 KB

english, 1998

17

Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide

Kourosh Lotfi, Emma Månsson, Joya Chandra, Yuying Wang, Dawei Xu, Eva Knaust, Tatjana Spasokoukotskaja, Eva Liliemark, Staffan Eriksson, Freidoun Albertioni

Journal:

British Journal of Haematology

Year:

2001

Language:

english

File:

PDF, 243 KB

english, 2001

18

Application of population pharmacokinetics to cladribine

Synnöve Lindemalm, Radojka M Savic, Mats O Karlsson, Gunnar Juliusson, Jan Liliemark, Freidoun Albertioni

Journal:

BMC Pharmacology

Year:

2005

Language:

english

File:

PDF, 1.11 MB

english, 2005

19

Protein binding of 2-chloro 2′-deoxyadenosine (cladribine) in healthy subjects and in patients with leukaemia

F. Albertioni, L. Herngren, G. Juliusson, J. Liliemark

Journal:

European Journal of Clinical Pharmacology

Year:

1994

Language:

english

File:

PDF, 202 KB

english, 1994

20

Intracellular concentrations of anti cancer drugs in leukemic cells in vitro vs in vivo

B. Sundman-Engberg, U. Tidefelt, J. Liliemark, C. Paul

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 498 KB

english, 1990

21

On the bioavailability of 2-chloro-2′-deoxyadenosine (CdA)

F. Albertioni, G. Juliusson, J. Liliemark

Journal:

European Journal of Clinical Pharmacology

Year:

1993

Language:

english

File:

PDF, 382 KB

english, 1993

22

Distribution of 2-chloro-2′-deoxyadenosine, 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine, Fludarabine and Cytarabine in mice: a whole-body autoradiography study

Synnöve Lindemalm, Jan Liliemark, Bengt S Larsson, Freidoun Albertioni

Journal:

Medical Oncology

Year:

1999

Language:

english

File:

PDF, 635 KB

english, 1999

23

Topoisomerase II-mediated alterations of K562 drug resistant sublines

R Zhou, Y Wang, A Gruber, R Larsson, E Castaños-Vèlez, E Liliemark

Journal:

Medical Oncology

Year:

1999

Language:

english

File:

PDF, 1.31 MB

english, 1999

24

Etoposide-induced DNA strand breaks in relation to p-glycoprotein and topoisomerase II protein expression in leukaemic cells from patients with AML and CLL

R. Zhou, S. Vitols, A. Gruber, J. Liliemark, Y. Wang, E. Liliemark

Journal:

British Journal of Haematology

Year:

1999

Language:

english

File:

PDF, 287 KB

english, 1999

25

Granulocyte-macrophage colony-stimulating factor to increase efficacy of mitoxantrone, etoposide and cytarabine in previously untreated elderly patients with acute myeloid leukaemia: a Swedish multicentre randomized trial

C. Löfgren, C. Paul, M. Åström, R. Hast, M. Hedenius, R. Lerner, J. Liliemark, I. Nilsson, S. Rödjer, B. Simonsson, D. Stockelberg, U. Tidefelt, M. Björkholm

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 204 KB

english, 2004

26

Oral etoposide in patients with hematological malignancies

E. Ösby, E. Liliemark, M. Björkholm, J. Liliemark

Journal:

Medical Oncology

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

27

Why Do Drugs Work in CLL?

Plunkett, W., Begleiter, A., Liliemark, J. O., Reed, J. C.

Journal:

Leukemia and Lymphoma

Year:

1996

Language:

english

File:

PDF, 788 KB

english, 1996

28

Kinetics and metabolism of 2-chloro-2′-deoxyadenosine and 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine in the isolated perfused rat liver

F. Albertioni, M. Hassan, J. Silberring, J. Liliemark

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

1995

Language:

english

File:

PDF, 674 KB

english, 1995

29

Fine-needle aspiration cytology and immunocytochemistry of malignant non-Hodgkin's lymphoma in the oral cavity

Jan Liliemark, Edneia Tani, Hakan Mellstedt, Lambert Skoog

Journal:

Oral Surgery, Oral Medicine, Oral Pathology

Year:

1989

Language:

english

File:

PDF, 1.84 MB

english, 1989

30

Increasing the accumulation of daunorubicin in human leukemic cells by prolonging the infusion time

Christer Paul, Ulf Tidefelt, Jan Liliemark, Curt Peterson

Journal:

Leukemia Research

Year:

1989

Language:

english

File:

PDF, 481 KB

english, 1989

31

On the biochemical modulation of 6-mercaptopurine by methotrexate in murine WEHI-3b leukemia cells in vitro

Jan Liliemark, Birgitta Pettersson, Curt Peterson

Journal:

Leukemia Research

Year:

1992

Language:

english

File:

PDF, 490 KB

english, 1992

32

Pharmacokinetics of mitoxantrone, etoposide and cytosine arabinoside in leukemic cells during treatment of acute myelogenous leukemia—Relationship to treatment outcome and bone marrow toxicity

Astrid Gruber, Eva Liliemark, Ulf Tidefelt, Christer Paul, Magnus Björkholm, Curt Peterson, Jan Liliemark

Journal:

Leukemia Research

Year:

1995

Language:

english

File:

PDF, 441 KB

english, 1995

33

Reduced DNA ligase activity in etoposide resistant human lymphatic leukaemia CEM cells

Eva Fredriksson, Eva Liliemark, Anya Polischouk, Stefan Söderhäll, Freidoun Albertioni, Siv Ljungquist

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 129 KB

english, 2002

34

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance

Emma Månsson, Emma Flordal, Jan Liliemark, Tatiana Spasokoukotskaja, Howard Elford, Svetlana Lagercrantz, Staffan Eriksson, Freidoun Albertioni

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 275 KB

english, 2003

35

In vitro topo II–DNA complex accumulation and cytotoxicity of etoposide in leukaemic cells from patients with acute myelogenous and chronic lymphocytic leukaemia

Yuying Wang, Rong Zhou, Jan Liliemark, Astrid Gruber, Synnöve Lindemalm, Froudoun Albertioni, Eva Liliemark

Journal:

Leukemia Research

Year:

2001

Language:

english

File:

PDF, 97 KB

english, 2001

36

Characterization of Drug-Resistant Cell Lines by Comparative Genomic Hybridization

Katrin M Carlson, Astrid Gruber, Eva Liliemark, Rolf Larsson, Magnus Nordenskjöld

Journal:

Cancer Genetics and Cytogenetics

Year:

1999

Language:

english

File:

PDF, 392 KB

english, 1999

37

Long-term follow-up of patients ≥60 yr old with acute myeloid leukaemia treated with intensive chemotherapy : A randomised trial of aclarubicin vs. daunorubicin in combination with cytosine arabinoside and thioguanine

G. Öberg, A. Killander, M. Björeman, G. Gahrton, G. Grimfors, A. Gruber, R. Hast, R. Lerner, J. Liliemark, S. Mattson, C. Paul, B. Simonsson, A.-M. Stalfelt, L. Stenke, U. Tidefelt, A.-M. Udén, M. Bjö

Journal:

European Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

38

Phosphorylation of 2-chlorodeoxyadenosine (CdA) in extracts of peripheral blood mononuclear cells of leukaemic patients

Elias S. J. Arner, Tatjana Spasokoukotskaja, Gunnar Juliusson, Jan Liliemark, Staffan Eriksson

Journal:

British Journal of Haematology

Year:

1994

Language:

english

File:

PDF, 360 KB

english, 1994

39

Low-dose cladribine for symptomatic hairy cell leukaemia

Gunnar Juliusson, Rodica Lenkei, Geir Tjønnfjord, Dag Heldal, Jan Liliemark

Journal:

British Journal of Haematology

Year:

1995

Language:

english

File:

PDF, 262 KB

english, 1995

40

PHARHACOKINETIC STUDIES ON ARA-C : With Special Emphasis on the Cellular Pharmacokinetics

Journal:

European Journal of Haematology

Year:

1986

Language:

english

File:

PDF, 447 KB

english, 1986

41

On the interaction between cytosine arabinoside and etoposide in vivo and in vitro

Jan Liliemark, Eva Knochenhauer, Astrid Gruber, Birgitta Pettersson, Magnus Björkholm, Curt Peterson

Journal:

European Journal of Haematology

Year:

1993

Language:

english

File:

PDF, 382 KB

english, 1993

42

Mitoxantrone, etoposide and ara-C vs doxorubicin-DNA, ara-C, thioguanine, vincristine and prednisolone in the treatment of patients with acute myelocytic leukaemia. A randomized comparison

M. Björkholm, J. Liliemark, G. Gahrton, G. Grimfors, A. Gruber, R. Hast, G. Juliusson, M. Jämmark, A. Killander, E. Kimby, R. Lerner, P. Ljungman, B. Lönnqvist, J. Palmblad, C. Paul, C. Petterson, B.

Journal:

European Journal of Haematology

Year:

1995

Language:

english

File:

PDF, 455 KB

english, 1995

43

Ultrafiltration and subsequent high performance liquid chromatography for in vivo determinations of the protein binding of etoposide

Eva Liliemark, Lars Herngren, Birgitta Pettersson, Curt Peterson, Jan Liliemark

Journal:

Year:

1996

Language:

english

File:

PDF, 691 KB

english, 1996

44

DNA damage induced by etoposide; a comparison of two different methods for determination of strand breaks in DNA

Solveig A.S. Walles, Rong Zhou, Eva Liliemark

Journal:

Year:

1996

Language:

english

File:

PDF, 594 KB

english, 1996

45

Higher in vivo protein binding of etoposide in children compared with adult cancer patients

Eva Liliemark, Stefan Söderhäll, Florin Sirzea, Astrid Gruber, Eva Ösby, Magnus Björkholm, Rong Zhou, Curt Peterson, Jan Liliemark

Journal:

Year:

1996

Language:

english

File:

PDF, 349 KB

english, 1996

46

Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues

T. Spasokoukotskaja, E.S.J. Arnér, O. Brosjö, P. Gunvén, G. Juliusson, J. Liliemark, S. Eriksson

Journal:

European Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

47

Cytotoxicity and pharmacokinetics of cladribine metabolite, 2-chloroadenine in patients with leukemia

Synnöve Lindemalm, Jan Liliemark, Gunnar Juliusson, Rolf Larsson, Freidoun Albertioni

Journal:

Year:

2004

Language:

english

File:

PDF, 122 KB

english, 2004

48

395 - Cladribine (CdA) therapy in chronic lymphocytic leukemia (CLL) - Long-term follow-up of 117 patients

Gunnar Juliusson, Mats Strömberg, Jan Liliemark

Journal:

European Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 355 KB

english, 1997

49

Response to 2-Chlorodeoxyadenosine in Patients with B-Cell Chronic Lymphocytic Leukemia Resistant to Fludarabine

Juliusson, Gunnar, Elmhorn-Rosenborg, Annika, Liliemark, Jan

Journal:

Boston Medical and Surgical Journal

Year:

1992

Language:

english

File:

PDF, 2.47 MB

english, 1992

50

Should regulators be concerned with pharmacoeconomic issues?

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 33 KB

english, 2007

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